Art has always been a part of Clayton’s life. When her eight children were young, she taught art classes, experimented in costuming and set design, and provided artwork for their school events. Since becoming blind due to macular degeneration, she has revised her focus from two-dimensional works to sculpture and paper mâché. Following her diagnosis, Clayton’s strong will and determination inspired her to continuously improve her art’s quality. As a mother, grandmother, and daycare provider for twenty-five years, Clayton’s love of children is apparent in her work. She has exhibited work in the National Exhibits of Blind Artists, the Wills Eye Hospital and the Philadelphia Museum of Art. She has also exhibited in Art Ability every year since 1997. In 2008, she won third place in the sculpture category for her piece Totem.